Hawthorn Berry Extract.Hawthorn Leaf Extract.
Serie No:S041.
Specifications:Berry Hydro-Alcoholic Extract:10:1 TLC;Leaf Extract:Vitexin-2"-O-rhamnoside 2%HPLC.
INCI Name:CRATAEGUS MONOGYNA EXTRACT
EINECS/ELINCS No.:289-914-0
CAS:90045-52-6
Chem/IUPAC Name:Crataegus Monogyna Extract is an extract of the berries of the crataegus, Crataegus monogyna, Rosaceae
Applications:
Antioxidant.
Cardiac Activity.
Early stages of heart disease.
Congestive heart failure.
Anti-inflammatory Action.
Atherosclerosis.
Chest pain.
CNS Actions(central nervous system).
High cholesterol.
Hypolipidemic Action.
High blood pressure.
Hypotensive Action.
Soothing effect.
Properties:
Used to promote the health of the circulatory system, treat angina, high blood pressure, congestive heart failure and cardiac arrhythmia and has been found to strengthen the heart. Hawthorn is widely regarded in Europe as a safe and effective treatment for the early stages of heart disease and has been used for a number of ailments including angina, myocarditis, arteriosclerosis, nervous conditions like insomnia, and diarrhea. It has also been indicated for strengthening blood vessels, vascular insufficiency and blood clots, restoring the heart muscle wall, lowering cholesterol and to aid digestion.
Dosage:extract suggested 500~2000mgs daily for general health conditions.
Safety and Toxicity:
Safety and Acute toxicity (LD50):No toxicity has been directly related to Crataegus preparations. The acute parenteral toxicity (LD50), tested in different animals, was found in a range of 18+-4 mL/kg, with that of individual constituents ranging from 50-2,600 mg/kg. The acute oral toxicity was reported to be in a range of 18.5+-3.8 mL/kg and 6 g/kg, respectively. In humans, therapeutic doses of hawthorn did not have adverse effects. However, drug interactions are likely with other cardiovascular agents, generating unwanted synergetic effects. Hawthorn can potentiate cardiac glycoside action of digitalis (or other related drugs, such as digitoxin, digoxin, or gitalin). Patients who take these drugs should consult with a medical professional before taking hawthorn.
