isosorbide dinitrate
Synonyms: IMDUR;IS-5-MN;ISOSORBIDE MONONITRATE;ISOSORBIDE 5-MONONITRATE;ISOSORBIDE 5-NITRATE;ELANTAN;ELAN;CORANGIN
CAS: 16051-77-7
MF: C6H9NO6
MW: 191.14
EINECS: 240-197-2
Product Categories: chiral;Nitric Oxide Reagents;Various Metabolites and Impurities;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;API's
Mol File: 16051-77-7.mol
mp 88-93
alpha 170 (c=1, EtOH)
refractive index 145 (C=5, H2O)
Water Solubility soluble
Merck 5225
Hazard Codes Xi-F,Xi,F
Risk Statements 36/37/38-11
Safety Statements 37/39-16-15
RIDADR 3251
RTECS LZ4386500
HazardClass 1.1A
Chemical Properties white to light yellow crystal powde
Usage A metabolite of Isosorbide Dinitrate. Used as an antianginal
General Description Isosorbide 5-mononitrate is a crystalline solid. Isosorbide 5-mononitrate is very flammable and may be toxic by ingestion.
Air & Water Reactions Highly flammable.
Fire Hazard Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished.
Usage: Isosorbide dinitrate (ISDN) (also known as Dilatrate) is a nitrate used pharmacologically as a vasodilator, e.g. in angina pectoris but also for anal fissure, a condition which is known to involve decreased blood supply leading to poor healing. It is also used as a direct vasodilator to treat congestive heart failure.
