Levonorgestrel CAS: 797-63-7
Product Name: Levonorgestrel
CAS: 797-63-7
MF: C21H28O2
MW: 312.45
EINECS: 212-349-8
mp: 206°C
storage temp: 2-8°C
appearance: White Solid
Description:
Levonorgestrel is a second generation progestin used as an active ingredient in some hormonal contraceptives, including combined oral
contraceptive pills, progestogen only pills, emergency contraceptive pills, intrauterine systems, contraceptive implants, and hormone replacement
therapy.
Application:
1.Oral contraception
At low doses, levonorgestrel is used in monophasic and triphasic formulations of combined oral contraceptive pills, with available monophasic
doses ranging from 100-250 μ G, and triphasic doses of 50 μ G/75 μ G/125 μ G.
At very low daily dose of 30 μ G, levonorgestrel is used in some progestogen only pill formulations.
2.Emergency contraception
Levonorgestrel is used in emergency contraceptive pills (ECPs), both in a combined Yuzpe regimen which includes estrogen, and as a levonorgestrel
-only method. The levonorgestrel-only method uses levonorgestrel 1.5 mg (as a single dose or as two 0.75 mg doses 12 hours apart) taken within 3
days of unprotected sex, with one study indicating that beginning as late as 120 hours (5 days) after intercourse could be effective.
3.Intrauterine system
Levonorgestrel is the active ingredient in the Mirena & Skyla (Jaydess) intrauterine system.
4.Contraceptive implants
Levonorgestrel is the active ingredient in Norplant and Jadelle.
5.Hormone replacement therapy
Levenorgestrel is combined with 17-beta estradiol in the Climara Pro hormonal patch.
