Vardenafil / Levitra CAS: 224785-91-5
Product Name: Vardenafil
Other Nmae: levitra
CAS: 224785-91-5
MF: C23H33ClN6O4S
MW: 525.06
mp: 214-216°C
appearance: White to Off-White Cyrstalline Solid
Description:
Vardenafil (INN) is a PDE5 inhibitor used for treating erectile dysfunction. Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors. The difference between the vardenafil molecule and is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both and vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's.
Application:
Beyond its indications for erectile dysfunction, vardenafil may be effective in the treatment of premature ejaculation, where it may significantly increase the time from vaginal penetration to ejaculation.
Vardenafil, as with all PDE5 inhibitors, should not be used by men taking nitrate medications, because combining them with vardenafil might provoke potentially life-threatening hypotension (low blood pressure).
Further, Vardenafil causing lengthening of the QT interval. Therefore it should not be taken by men taking other medications that affect the QT interval (such as amiodarone).
