Formestane CAS: 566-48-3
Product Name: Formestane
Synonyms: 4-OHA;CGP-32349
CAS: 566-48-3
MF: C19H26O3
MW: 302.41
mp: 199-202°C
storage temp: 2-8°C
form: solid
Density: 1.19g/cm3
Melting Point: 199-202° C
Boiling Point: 475.4° Cat760mmHg
Refractive Index: 1.545
Flash Point: 255.4° C
Description:
Formestane (Lentaron) is a type I, steroidal aromatase inhibitor. It is used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. It is available as an intramuscular depot injection.
Formestane is often used to suppress estrogen production from anabolic steroids or prohormones. It also acts as a prohormone to 4-hydroxytestosterone, an active steroid which displays weak androgenic activity in addition to acting as a mild aromatase inhibitor.
Formestane has poor oral bioavailability and as such is no longer popular as many orally active aromatase inhibitors have been identified.
