Milk Thistle Extract.Silymarin.
Serie No:S017.
Specifications:Silymarin 80%UV (DAB-10),Silymarin 70%HPLC (DAB-10).
INCI Name:SILYBUM MARIANUM EXTRACT
EINECS/ELINCS No.:283-298-7
CAS:84604-20-6
Chem/IUPAC Name:Silybum Marianum Extract is an extract of the seeds and leaves of the lady's thistle,Silybummarianum,Compositae.
Applications:
Inhibitor of Beta-glucuronidase.
Anti Free radicals.
Hepatoprotective,Liver injury protection of silymarin.
Silymarin reduced lipoperoxidative hepatic damage.
Silymarin proved against hepatotoxicity.
Promotes milk secretion,treat lactation problems,prevent cancer.
Properties:
A number of studies have suggested that silymarin is an anti-inflammatory. It regulates inflammatory mediators such as tumor necrosis factor (TNF), TNF-alpha, nitrous oxide, interleukin-, and interleukin-1 receptor antagonist. Silymarin also increases lymphocyte proliferation, interferon gamma, interleukin-, and interleukin- cytokines, in a dose-dependent manner. Taken together, these effects suggest a possible role in preventing or treating infectious disease.
Dosage: For standardized extract, 200-400 mg of silymarine per day is recommended.
Safety and Toxicity:
Acute toxicity(LD50):Silymarin.LD50-Lethal dose,50 percent kill. Intravenous.Rodent-mouse.>1600 mg/kg.Details of toxic effects not reported other than lethal dose value.
